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How Much Did Guardant Health Raise? Headquarters, Funding & Key Investors

Guardant Health, founded in 2012 by AmirAli Talasaz, has raised $557M across private and public financings, including a $360M Series E in 2017 and later IPO placements. The company develops liquid biopsy technologies, enabling tumor DNA sequencing from blood for precision oncology, therapy selection, and clinical trial matching. Funding supported R&D, clinical validation, commercial scaling, and pharma partnerships. Employing around 1,351 people, Guardant Health accelerates adoption of non-invasive genomic testing. Investors include Lightspeed Venture Partners, Sequoia Capital, SoftBank Vision Fund, OrbiMed, and Khosla Ventures, positioning the company as a leader in oncology diagnostics and liquid biopsy innovation.

    Guardant Health joined the Unicorn Club after raising multiple rounds, including a $360M Series E in 2017, reaching total funding of $557M. Headquartered in Redwood City, California, United States, Guardant Health provides liquid biopsy technologies for precision oncology, enabling non-invasive tumor DNA sequencing to guide therapy selection and clinical trial enrollment for oncologists and pharmaceutical partners.

    Keep reading to learn how Guardant Health advances cancer diagnostics and precision oncology solutions.

    What Is Guardant Health and What Does It Do?

    Founded in 2012 by AmirAli Talasaz, Guardant Health is a Redwood City–based precision oncology company offering liquid biopsy sequencing and diagnostics. The company employs approximately 1,351 people and delivers blood-based genomic tests, clinical reporting, and trial-enabling services for oncologists and pharma partners.

    Guardant Health’s technology uses circulating tumor DNA to profile mutations and resistance markers, enabling faster sample collection and turnaround compared with tissue biopsies. The platform supports therapy selection, disease monitoring, and clinical trial matching, while revenue comes from clinical testing, pharma partnerships, and lab services.

    How Much Funding Has Guardant Health Raised?

    1. Post IPO (Nov 05, 2025)

    • Amount Raised: $350M
    • Date: Nov 05, 2025
    • Lead Investors: Public market participants
    • Purpose: Commercial scale and international expansion

    2. Post IPO (Nov 16, 2020)

    • Amount Raised: $1B
    • Date: Nov 16, 2020
    • Lead Investors: Institutional placements
    • Purpose: Growth of testing footprint and pharma partnerships

    3. Series E

    • Amount Raised: $360M
    • Date: Aug 09, 2017
    • Lead Investors: SoftBank Vision Fund, Sequoia Capital, Khosla Ventures, Lightspeed
    • Purpose: R&D scale and clinical validation

    Total Funding Raised: $557M
    Latest Funding Date: Nov 2025
    Latest Known Valuation: Public market valuation fluctuates

    Key Investors

    1. Lightspeed Venture Partners
      • Details: VC with medtech and healthcare investments
      • Focus Areas: Diagnostics, healthtech, biotech
      • Notable Investments: Guardant Health, Snap (select), other health tech firms
    2. Sequoia Capital
      • Details: Top VC investing across sectors, including healthcare
      • Focus Areas: Biotech, diagnostics, enterprise health
      • Notable Investments: Guardant Health, Airbnb (select), others
    3. SoftBank Vision Fund
      • Details: Large growth fund investing in category-defining companies
      • Focus Areas: Platform-scale health and AI
      • Notable Investments: Guardant Health participation, various tech giants
    4. OrbiMed
      • Details: Healthcare-focused investment firm backing biotech and diagnostics
      • Focus Areas: Biotech, diagnostics, pharma partnerships
      • Notable Investments: Guardant Health, multiple biotech companies
    5. Khosla Ventures
      • Details: VC with healthcare and deep tech focus
      • Focus Areas: Biotechnology, diagnostics, medtech
      • Notable Investments: Guardant Health, Impossible Foods (select), other deep tech bets

    Where Is Guardant Health’s Headquarters?

    Guardant Health is headquartered in Redwood City, California, United States, near major biotech clusters and clinical partners.

    What’s Next for Guardant Health?

    Guardant Health plans to scale global testing, deepen pharma R&D partnerships for companion diagnostics, improve assay sensitivity, and expand into earlier cancer detection and monitoring.

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